why does glp 1 not work for some people GLP-1 Agonists - What is it? Why GLP-1 Drugs Work Better

The clinical backdrop matters too

The secondary endpoint of fibrosis reduction by at least one stage was documented in 34%, 36%, and 34% of participants receiving survodutide compared to 22% of placebo, demonstrating potential anti-fibrotic benefit [23]

Semaglutide targets the GLP-1 receptor, while Tirzepatide targets both GLP-1 and GIP receptors

It has been shown that GLP-1RA semaglutide can improve working and spatial memory in transgenic AD modelling APP/PS1/tau (3xTg) mice, promote the release of anti-inflammatory factors and inhibit the production of pro-inflammatory factors in the cerebral cortex and hippocampus, as well as reduce the deposition of -amyloid in the CA1 subfield of the hippocampus