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In contrast, metabolites connecting multiple pathways, such as DHAP, common to both the PPP and glycolysis, and OAA, common to the both TCA and glycolysis, correlated with SLEDAI, BILAG, and FAS scores, suggesting that increased flux among these pathways are involved in disease activity
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Abstract Background Smoking tobacco is a leading cause of chronic obstructive pulmonary disease (COPD), but although the majority of COPD cases can be directly related to smoking, only a quarter of smokers actually develop the disease
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