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[19] [1] This washout period allows for adequate drug clearance and minimizes potential fetal exposure during early pregnancy

The global prevalence of 537 million affected in the age group of 2079 years in 2021 will rise to 783 million in 2045, with the lowest increase in incidence in Europe (13%) and the highest in the African countries south of the Sahara (134%) ( Obesity, defined as a body mass index above 30 kg/m 2 , is also increasingly prevalent worldwide and has become a challenge to the various healthcare systems and societies

But the expanded MACE endpoint, which added coronary revascularization, showed a statistically significant 12% reduction with tirzepatide (HR 0.88)

Eating slowly and chewing food thoroughly allows better recognition of satiety signals and prevents overfilling the stomach