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Among those aged 1544 years, model-based estimates indicate that the prevalence of current smoking declined from 35.5% (95% CI: 30.640.7%) in 1997 to 20.8% (95% CI: 15.327.5%) in 2025, and is projected to decrease further to 16.0% (95% CI: 9.425.8%) by 2040

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Invading microorganisms can be sensed through specific pathogen-associated molecular patterns recognized by pathogen recognition receptors on DCs, such as Toll-like receptors (TLRs), C-type lectin receptors, cytosolic Nod-like receptors, and rig-like receptors