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Therapeutic strategies targeting this axis (Figure 2), such as BH4 supplementation, NOX inhibitors, and lifestyle modifications (e.g., exercise, Mediterranean diet), aim to restore redox balance and endothelial function, though their efficacy varies by HTN stage and comorbidities

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Consistent use of almond oil can improve skin clarity, reduce the appearance of dark spots, and even out the complexion, making it a valuable addition to natural melanin reduction routines