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Oxidative stress and hypoxia modify mitochondrial homeostasis during glaucoma

Parental ZR-75-1 cells were cultured in Phenol-red free medium containing 10% Dextran-coated charcoal-stripped FBS (DCC) with increasing concentration of Tamoxifen, starting from 0.5 M initially, and finally up to 5 M in a period of about 6 months

[PubMed] [Google Scholar] Graham 2007 Graham ID, Jette N, Tetroe J, Robinson N, Milne S, Mitchell SL

The Institutional Breeding House in Cairo, Egypt, provided the animals, which were then acclimated to standard laboratory conditions of a 12-hour light/dark cycle (lights on from 6:00 AM to 6:00 PM), 60% humidity, and 25 C