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If heart failure occurs, dosage reduction or discontinuation of TZD must be considered

Collectively, these data highlight the importance of integrating metabolic health into early therapeutic strategies for PsA, particularly in individuals at high risk of disease progression or in those presenting with subclinical musculoskeletal involvement

J Allergy Clin Immunol 118 : 12181225 Fitzpatrick AM, Teague WG, Holguin F, Yeh M, Brown LA, Severe Asthma Research Program 2009 Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress

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