what amount is a microdose of semaglutide Everybody’s MICRODOSING and Tirzepatide! Is 'Microdosing' Ozempic Safe?

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Highest dose, obesity trial obesity-plus-diabetes trial (treatment-policy estimand): Semaglutide: 14.9% (STEP 1) 9.6% (STEP 2), a 5.3 point gap Tirzepatide: 20.9% (SURMOUNT-1) 14.7% (SURMOUNT-2), a 6.2 point gap Retatrutide: 25.0% (TRIUMPH-1) 20.8% (TRIUMPH-2 only efficacy-estimand currently reported so true gap is larger) It's still unclear the reason why we observe less weight loss in those with T2D

The bottom line is that weight loss reduces the risk and severity of Sleep Apnea, but the drugs are not the holy grail to eliminating this debilitating and dangerous disease