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Dysregulated mTORC1 and TFEB signaling exacerbate these autophagic defects, prompting research into the use of autophagy modulators as potential therapeutic strategies [144, 146]

ACS Appl Mater Interfaces 15:3121431223

B-complex vitamins, vitamin C, and glutathione are common ingredients that may help support energy production and immune function

While conceptually different than active site mutagenesis, metagenomic domain substitution offers an alternative approach to generate protein sequence diversity